USA Road Trip Itinerary: Epic 10-Day Route Across the West Coast

Why This Trip is the Dream

Ever stared at a map of the U.S. West Coast and thought, “How the heck do I see all this without living in my car for six months?” Yep, I’ve been there too. The West Coast is massive, full of bucket-list spots, and way too tempting to ignore. But here’s the good news: you don’t need months off work (or a lottery win) to explore it.

With a 10-day USA road trip itinerary, you can cover epic cities, jaw-dropping national parks, and those quirky roadside stops you’ll still be laughing about years later. And trust me, I’ve done versions of this trip — from sleeping in the back of a rental car (don’t recommend) to treating myself with proper hotels — and this is the ultimate balance of adventure + chill.

So buckle up (literally), because this 10-day West Coast road trip itinerary is going to give you all the stops, pro tips, and those little hacks that make the difference between “fun adventure” and “are we there yet?” meltdown.

Day 1: San Francisco — Golden Gate Vibes & City Charm

Start in San Francisco, because honestly, is it even a West Coast trip if you don’t?

Must-Sees:

  • Golden Gate Bridge (obviously). Pro tip: skip the crowded vista points and go to Battery Spencer for epic views.
  • Fisherman’s Wharf for clam chowder in sourdough bread bowls.
  • Alcatraz Island if you’re into history (or creepy vibes).
Travel Hack: Park your car at your hotel and use public transport or Uber for the day. Driving in San Francisco is like playing Mario Kart on expert mode… with fewer bananas and more angry honking.

Day 2: San Francisco → Yosemite National Park

Time to swap city life for pure wilderness. It’s about a 4-hour drive from San Francisco to Yosemite.

Why Go: Yosemite is one of those places that makes you say, “Okay, nature, I get it — you win.” The granite cliffs, waterfalls, and giant sequoias feel unreal.

Must-Sees:

  • El Capitan (yep, the one from “Free Solo”).
  • Half Dome — hike it if you’re feeling hardcore, or admire from the valley if you’re more of a picnic person.
  • Yosemite Falls in spring = chef’s kiss.
Hack: Book your Yosemite lodging months in advance, or stay just outside the park in Mariposa or Oakhurst for cheaper rates.

Day 3: Yosemite → Sequoia National Park

Next stop: trees so big you’ll feel like a Lego figure. Drive south (about 4 hours) to Sequoia National Park.

Must-Sees:

  • General Sherman Tree (largest tree in the world by volume).
  • Moro Rock climb = insane panoramic views.
  • Tunnel Log — yes, you can drive through a tree. Bucket list: checked.
Personal Tip: I once picnicked here and a squirrel straight-up stole half my sandwich. Moral of the story? Don’t trust the squirrels.

Day 4: Sequoia → Los Angeles

After nature overload, head toward Los Angeles (about 4.5 hours). The city is chaotic but iconic.

Must-Sees:

  • Hollywood Sign Hike (take the Brush Canyon Trail if you want fewer tourists).
  • Santa Monica Pier for carnival vibes.
  • Venice Beach — weird, wonderful, and perfect for people-watching.
Hack: LA traffic is a beast. Avoid rush hour (aka 7–10 am and 4–7 pm), or you’ll spend more time staring at bumpers than beaches.

Day 5: Los Angeles → San Diego

Cruise down the Pacific Coast Highway to San Diego (about 2–3 hours).

Why Go: Chill vibes, perfect weather, and some of the best tacos in the U.S.

Must-Sees:

  • Balboa Park (gardens + museums + free performances).
  • La Jolla Cove for sea lions.
  • Gaslamp Quarter for nightlife.
Foodie Hack: Don’t miss fish tacos at Oscar’s or Lolita’s. Trust me, you’ll dream about them later.

Day 6: San Diego → Joshua Tree National Park

Drive east (about 3 hours) into the desert magic of Joshua Tree.

Why Go: Surreal landscapes that look straight out of a Dr. Seuss book. Plus, stargazing here = unreal.

Must-Sees:

  • Skull Rock
  • Keys View at sunset
  • Joshua trees themselves (you’ll recognize them instantly).
Hack: Stay in a funky Airbnb in Joshua Tree town — they’ve got everything from Airstreams to desert domes.

Day 7: Joshua Tree → Las Vegas

From desert calm to neon chaos, it’s a 3-hour drive to Las Vegas.

Must-Sees:

  • Walk the Strip at night. Even if you’re not a gambler, it’s a wild experience.
  • Bellagio Fountains (free and worth it).
  • A quick day trip to Red Rock Canyon if the city feels like too much.
Personal Tip: I once lost $20 in 3 minutes at blackjack, so IMO the real win is hitting a buffet and calling it a night.

Day 8: Las Vegas → Grand Canyon National Park

Drive about 4 hours to Grand Canyon (South Rim).

Why Go: It’s the Grand Freaking Canyon. Pictures don’t do it justice.

Must-Sees:

  • Mather Point for sunrise.
  • Bright Angel Trail if you’re up for a hike.
  • Rim Trail for easy, stunning walks.
Hack: Bring snacks and water. The overpriced food at the rim will hurt your wallet more than the canyon hurt the Colorado River.

Day 9: Grand Canyon → Death Valley National Park

Head west again, about 5 hours to Death Valley, the hottest, driest, lowest spot in North America. Sounds inviting, right? Actually, it’s amazing.

Must-Sees:

  • Badwater Basin (salt flats that look like another planet).
  • Zabriskie Point for sunrise.
  • Mesquite Flat Sand Dunes — you’ll feel like you’re in Star Wars.
Hack: Visit in spring or fall unless you want to roast alive. Also, gas up before entering the park. Prices inside = ouch.

Day 10: Death Valley → San Francisco (Loop Complete)

Finish the loop with a long drive back to San Francisco (about 7 hours). It’s a full-circle ending, and you’ll probably need a nap… or three.

Optional Add-On: If you’ve got extra time, detour through Lake Tahoe for mountain vibes and clear blue waters.

Extra Travel Hacks for Your West Coast Road Trip

Because what’s a road trip without some pro hacks?

  • Download Offline Maps: Cell service disappears in parks. Don’t rely on Google to save you.
  • Buy a National Parks Pass: At $80, it pays for itself after 3 parks.
  • Pack Snacks Like a Parent: Granola bars save lives (or at least moods).
  • Spotify Playlists > Radio: Some stretches have zero stations. Unless you enjoy static, make playlists in advance.
  • Car Organization = Sanity: Trunk organizers and reusable grocery bags are lifesavers.

Where to Stay Along the Way

Mix it up:

  • Cities: Budget hotels or funky hostels.
  • National Parks: Campsites, cabins, or nearby motels.
  • Quirky Stops: Airbnbs with character (Joshua Tree is full of them).
Tip: I book most of my stays on Booking.com because free cancellation = peace of mind. Plans change, and this trip has plenty of moving parts.

Final Thoughts: Your Epic West Coast Road Trip Awaits

So there you have it — a 10-day USA road trip itinerary across the West Coast that hits cities, national parks, beaches, and even a few casinos (just don’t blame me if your $20 disappears in Vegas).

Here’s the truth: road trips aren’t about racing through a checklist. They’re about blasting your favorite music, eating questionable snacks at gas stations, and collecting memories that make you laugh years later.

So grab your keys, a travel buddy (or go solo, you rebel), and hit the road. The West Coast is waiting — and trust me, it’s epic.

Ready to plan your stays? Check out deals on Booking.com — because nothing kills road trip vibes like scrambling for a motel at midnight.